Simufilam dihydrochloride
Simufilam dihydrochloride is an orally bioavailable small molecule that selectively binds to misfolded filamin A (FLNA) in Alzheimer's disease research. It restores FLNA's normal function, which has been shown in experimental models to improve synaptic signaling and reduce neuroinflammation by disrupting pathological protein interactions.
Product Specifications
CAS Number
2480226-06-8
Product Name Alternative
A7nAChR, inhibit, Inhibitor, PTI125, PTI-125, PTI125 Dihydrochloride, PTI-125 Dihydrochloride, PTI-125 dihydrochloride, PTI 125, PTI 125 Dihydrochloride, Simufilam, Simufilam dihydrochloride, Simufilam Dihydrochloride
Field of Research
Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
DMSO:65 mg/mL (195.61 mM)
Smiles
[H]Cl.O=C1N (CC2=CC=CC=C2) C3 (CCN (C) CC3) NC1.[H]Cl
Molecular Formula
C15H23Cl2N3O
Molecular Weight
332.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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