BIIB068
BIIB068 is a potent, selective, and orally bioavailable reversible inhibitor of Bruton's tyrosine kinase (BTK), exhibiting an IC50 of 1 nM and high kinase selectivity. It is a valuable research tool for investigating BTK's role in B-cell malignancies and autoimmune disorders in both cellular and animal models.
Product Specifications
CAS Number
1798787-27-5
Product Name Alternative
Inhibit, FcγR, Inhibitor, anti-IgD, anti-IgM, Autoimmune, Bruton tyrosine kinase, BIIB068, BIIB-068, BIIB 068, Btk, BTK, ADME, ROS, reversible, phosphorylation, TNFα
Field of Research
Cardiovascular Research, Signal Transduction
Purity
97.98% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.59 mM) ; DMSO:30 mg/mL (68.88 mM)
Smiles
CC (C) OC1CN (C1) C (=O) NCc1ccc (cc1C) -c1ccnc (Nc2cnn (C) c2) n1
Molecular Formula
C23H29N7O2
Molecular Weight
435.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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