UMB298
UMB298 is a potent and selective small-molecule inhibitor targeting the CBP/P300 bromodomains. It exhibits significantly lower activity against BRD4 (IC50 = 5193 nM) . This compound is a valuable chemical probe for epigenetic research, facilitating the study of CBP/P300 function in transcriptional regulation in both cellular and biochemical assays.
Product Specifications
CAS Number
2266569-73-5
Product Name Alternative
CBP30, BRD4, bromodomain, inhibit, Inhibitor, MOLM13, EpigeneticReaderDomain, Epigenetic Reader Domain, selective, potent, UMB298, UMB-298, UMB 298
Field of Research
Epigenetics & Chromatin
Purity
99.76% (May vary between batches)
Solubility
DMSO:20 mg/mL (41.75 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.18 mM)
Smiles
COc1ccc (CCc2nc3cc (ccn3c2NC2CCCCC2) -c2c (C) noc2C) cc1Cl
Molecular Formula
C27H31ClN4O2
Molecular Weight
479.01
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
CSAG2, NT (CSAG2, TRAG3, Chondrosarcoma-associated gene 2/3 protein, Cancer/testis antigen 24.2, Taxol-resistant-associated gene 3 protein) (MaxLight 550) discontinued