JH-X-119-01
JH-X-119-01 is a potent, selective, and irreversible small molecule inhibitor targeting IRAK-1 kinase. It is a valuable research tool for investigating TLR/IL-1R signaling pathways in immunological and inflammatory disease models, applicable in both cellular and in vivo studies.
Product Specifications
CAS Number
2227368-54-7
Product Name Alternative
Waldenstr?m, JH X 119 01, JHX11901, JH-X-119-01, inhibit, MYD88, Interleukin-1 receptor associated kinase, IL-1R associated kinase, IRAK, IRAK1, IRAK-1, macroglobulinemia, Inhibitor, Diffused Large B-cell Lymphoma
Field of Research
Immunology & Inflammation, Signal Transduction
Purity
97.10% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.21 mM) ; DMSO:12 mg/mL (26.52 mM)
Smiles
C=CC (=O) Nc1cccc (c1) C (=O) Nc1ccc (NC (=O) c2cccc (n2) -c2cc[nH]n2) cc1
Molecular Formula
C25H20N6O3
Molecular Weight
452.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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