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JH-X-119-01

JH-X-119-01 is a potent, selective, and irreversible small molecule inhibitor targeting IRAK-1 kinase. It is a valuable research tool for investigating TLR/IL-1R signaling pathways in immunological and inflammatory disease models, applicable in both cellular and in vivo studies.

Product Specifications

CAS Number

2227368-54-7

Product Name Alternative

Waldenstr?m, JH X 119 01, JHX11901, JH-X-119-01, inhibit, MYD88, Interleukin-1 receptor associated kinase, IL-1R associated kinase, IRAK, IRAK1, IRAK-1, macroglobulinemia, Inhibitor, Diffused Large B-cell Lymphoma

Field of Research

Immunology & Inflammation, Signal Transduction

Purity

97.10% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.21 mM) ; DMSO:12 mg/mL (26.52 mM)

Smiles

C=CC (=O) Nc1cccc (c1) C (=O) Nc1ccc (NC (=O) c2cccc (n2) -c2cc[nH]n2) cc1

Molecular Formula

C25H20N6O3

Molecular Weight

452.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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