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G140

G140 is a potent and selective small molecule inhibitor of the cGAS enzyme. It is a valuable research tool for investigating the cGAS-STING signaling pathway in both cellular and animal models of autoimmunity, inflammation, and cancer.

Product Specifications

CAS Number

2369751-07-3

Product Name Alternative

Anti-inflammatory, cyclic, Cyclic GMP-AMP Synthase, cGAS, inhibit, Inhibitor, GMP-AMP, G140, G-140, G 140, synthase

Field of Research

Immunology & Inflammation

Purity

98.16% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (13.18 mM) ; DMSO:247 mg/mL (651.3 mM)

Smiles

ClC1=C2C (C3=C (N2) CCN (C (CO) =O) C3) =C (C=C1Cl) C=4C=CN (C) N4

Molecular Formula

C17H16Cl2N4O2

Molecular Weight

379.24

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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