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USP7-IN-8

This small molecule, also known as USP7-IN-8 or GNE-6776, is a selective USP7 inhibitor with an IC50 of 1.4 μM. It exhibits anticancer properties and is a valuable chemical probe for studying deubiquitinase biology in cancer research, both in vitro and in vivo.

Product Specifications

CAS Number

2009273-60-1

Product Name Alternative

Deubiquitinase, DUBs, anticancer, Inhibitor, inhibit, GNE6776, GNE-6776, GNE 6776, USP7 IN 8, USP7IN8, USP-7-IN-8, USP7-IN-8, USP7

Field of Research

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry

Purity

98.48% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.5 mM) ; DMSO:80 mg/mL (230.28 mM)

Smiles

CCc1c (cnc (N) c1-c1ccc (O) cc1) -c1ccc (cc1) C (=O) NC

Molecular Formula

C21H21N3O2

Molecular Weight

347.41

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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