Val-Ala-PAB
Val-Ala-PAB is a key synthetic intermediate for the pyrrolobenzodiazepine dimer payload Tesirine (SG3249), used in antibody-drug conjugates. This cleavable linker-payload building block enables the construction of targeted cancer therapeutics, supporting research in ADC development and preclinical in vitro and in vivo efficacy studies.
Product Specifications
CAS Number
1343476-44-7
Product Name Alternative
ADC Linker, ADCLinker, ValAlaPAB, Val-Ala-PAB, Val Ala PAB
Purity
98.07% (May vary between batches)
Solubility
DMSO:50 mg/mL (170.44 mM)
Smiles
CC (C) [C@H] (N) C (=O) N[C@@H] (C) C (=O) Nc1ccc (CO) cc1
Molecular Formula
C15H23N3O3
Molecular Weight
293.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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