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Fedratinib hydrochloride hydrate

Fedratinib hydrochloride hydrate is an orally bioavailable, selective, and ATP-competitive small molecule inhibitor of JAK2. It is widely used in preclinical research to investigate myeloproliferative neoplasms, demonstrating activity in both cellular assays and animal models of disease.

Product Specifications

CAS Number

1374744-69-0

Product Name Alternative

Anti-proliferation, Apoptosis, anti-cancer, Inhibitor, FLT3, Fedratinib hydrochloride, Fedratinib hydrochloride Hydrate, Fedratinib hydrochloride hydrate, orally, inhibit, JAK2, JAK, JAK2V617F, JAK2 (V617F), Janus kinase, myeloproliferative, phosphorylation, RET, SAR 302503 hydrochloride, SAR 302503 hydrochloride hydrate, SAR 302503 hydrochloride Hydrate, TG-101348 hydrochloride, TG-101348 hydrochloride hydrate, TG-101348 hydrochloride Hydrate, STAT5

Field of Research

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.96% (May vary between batches)

Solubility

DMSO:120 mg/mL (194.93 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (6.5 mM) ; H2O:97 mg/mL (157.57 mM)

Smiles

O.Cl.Cl.Cc1cnc (Nc2ccc (OCCN3CCCC3) cc2) nc1Nc1cccc (c1) S (=O) (=O) NC (C) (C) C

Molecular Formula

C27H40Cl2N6O4S

Molecular Weight

615.61

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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