(S) -Sunvozertinib
(S) -Sunvozertinib (DZD9008) is an irreversible, selective inhibitor targeting EGFR and HER2 tyrosine kinases. It is a research tool for investigating oncogenic mutations in preclinical models, demonstrating activity in both cellular assays and in vivo studies against EGFR-mutant cancers, including those with exon 20 insertions.
Product Specifications
CAS Number
2370013-49-1
Product Name Alternative
Btk, Bruton tyrosine kinase, (S) Sunvozertinib, (S) -DZD9008, (S) Sunvozertinib, (S) -Sunvozertinib, DZD 9008, DZD9008, DZD-9008, breast cancer, Epidermal growth factor receptor, ErbB-1, EGFR, HER2, HER1, Her2, Inhibitor, mutant forms of ErbB, inhibit, lung, N-[5-[[4-[5-Chloro-4-fluoro-2- (2-hydroxypropan-2-yl) anilino]pyrimidin-2-yl]amino]-2-[ (3S) -3- (dimethylamino) pyrrolidin-1-yl]-4-methoxyphenyl]prop-2-enamide, Sunvozertinib
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.64% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.42 mM) ; DMSO:55 mg/mL (94.17 mM)
Smiles
COc1cc (N2CC[C@@H] (C2) N (C) C) c (NC (=O) C=C) cc1Nc1nccc (Nc2cc (Cl) c (F) cc2C (C) (C) O) n1
Molecular Formula
C29H35ClFN7O3
Molecular Weight
584.08
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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