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Necroptosis-IN-1

Necroptosis-IN-1 is a potent, small-molecule inhibitor of RIPK1, functioning as a necroptosis inhibitor and an analog of Necrostatin-1. It is widely used in biochemical and cellular research to study programmed necrosis pathways in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

1391980-92-9

Product Name Alternative

Inhibit, Inhibitor, Necroptosis, Necroptosis IN 1, NecroptosisIN1, Necroptosis-IN-1, Receptor-interacting protein kinases, RIPK, RIPK1, RIPkinase, RIP kinase

Field of Research

Cell Biology, Signal Transduction

Purity

99.26% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (18.96 mM) ; DMSO:249 mg/mL (944.33 mM)

Smiles

Clc1cccc2c (CC3NC (=O) NC3=O) c[nH]c12

Molecular Formula

C12H10ClN3O2

Molecular Weight

263.68

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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