YK-3-237
YK-3-237 is a small molecule that decreases mutant p53 acetylation. It demonstrates anti-proliferative activity in triple-negative breast cancer (TNBC) cell lines harboring mutant p53, making it a useful research tool for investigating p53 biology and oncogenic signaling pathways in vitro.
Product Specifications
CAS Number
1215281-19-8
Product Name Alternative
Breast, cancer, B-[2-Methoxy-5-[ (1E) -3-oxo-3- (3,4,5-trimethoxyphenyl) -1-propen-1-yl]phenyl]boronic acid, Inhibitor, deacetylation, inhibit, Mutant, mtp53, p53, triple-negative, TNBC, Sirtuin, SIRT1, YK3237, YK-3-237, YK 3 237
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
96.38% (May vary between batches)
Solubility
Ethanol:10 mg/mL (26.87 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.37 mM) ; DMSO:30 mg/mL (80.61 mM) ; DMF:30 mg/mL (80.61 mM)
Smiles
COc1ccc (\C=C\C (=O) c2cc (OC) c (OC) c (OC) c2) cc1B (O) O
Molecular Formula
C19H21BO7
Molecular Weight
372.18
Storage Conditions
-20°C
Notes
For research use only.
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