Stafia-1
Stafia-1 is a selective small-molecule inhibitor of STAT5a with an IC50 of 22.2 μM, exhibiting high specificity over STAT5b and other STAT proteins. It is a valuable research tool for studying STAT5a-dependent signaling in leukemia and other cancers, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2582757-90-0
Product Name Alternative
Domain, cells, inhibit, Inhibitor, leukemia, STAT5a, Stafia 1, Stafia1, Stafia-1, STAT, selectivity, SH2
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Purity
98.08% (May vary between batches)
Solubility
DMSO:50 mg/mL (98.73 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.95 mM)
Smiles
O (P (=O) (O) O) C1=CC (=CC (=C1) C2=CC (OC) =C (OC) C (OC) =C2) C3=CC (OC) =C (OC) C (OC) =C3
Molecular Formula
C24H27O10P
Molecular Weight
506.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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