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Regorafenib Hydrochloride

Regorafenib Hydrochloride (BAY73-4506 hydrochloride) is an orally bioavailable, small-molecule multikinase inhibitor targeting key angiogenic, stromal, and oncogenic receptor tyrosine kinases. It demonstrates potent antitumor activity in preclinical models, supporting its research use in oncology for both in vitro mechanistic studies and in vivo efficacy experiments.

Product Specifications

CAS Number

835621-07-3

Product Name Alternative

CRET, BAY73-4506 Hydrochloride, BAY73-4506 hydrochloride, Autophagy, BAY 73-4506, inhibit, Platelet-derived growth factor receptor, PDGFR, Inhibitor, RET, Regorafenib, Regorafenib Hydrochloride, Raf-1, Raf kinases, Raf, VEGFR, Vascular endothelial growth factor receptor

Field of Research

Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Purity

99.56% (May vary between batches)

Solubility

DMSO:40 mg/mL (77.03 mM)

Smiles

Cl.CNC (=O) c1cc (Oc2ccc (NC (=O) Nc3ccc (Cl) c (c3) C (F) (F) F) c (F) c2) ccn1

Molecular Formula

C21H16Cl2F4N4O3

Molecular Weight

519.28

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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