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GKT136901

GKT136901 (AK120765) is a selective, direct peroxynitrite scavenger and a dual inhibitor of NOX1 and NOX4 enzymes. It is utilized in research to investigate oxidative stress pathways in models of fibrosis, inflammation, and cardiovascular disease, both in vitro and in vivo.

Product Specifications

CAS Number

955272-06-7

Product Name Alternative

Inhibitor, GKT 136901, GKT136901, GKT-136901, NOX, NOX1/4, NOX1, inhibit, neurodegeneration, nephropathy, NADPHoxidase, NADPH Oxidase, NADPH, oxidase, diabetic, AK 120765, AK120765, AK-120765, anti-inflammatory, stroke, scavenger, peroxynitrite

Field of Research

Immunology & Inflammation, Metabolism Research

Purity

98.29% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.45 mM) ; DMSO:32.5 mg/mL (88.6 mM)

Smiles

Cc1n (Cc2ccccn2) c (=O) cc2[nH]n (-c3ccccc3Cl) c (=O) c12

Molecular Formula

C19H15ClN4O2

Molecular Weight

366.8

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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