DCLK1-IN-1
DCLK1-IN-1 is a potent and selective chemical probe for DCLK1/2 kinase inhibition, with IC50 values in the low nanomolar range. This in vivo-compatible tool compound enables the investigation of DCLK1 biology and its functional roles in cancer models, both in vitro and in vivo.
Product Specifications
CAS Number
2222635-15-4
Product Name Alternative
Cancer, DCLK1IN1, DCLK-1-IN-1, DCLK1-IN-1, DCLK1 IN 1, PDAC, KRAS, inhibit, low, ERK, Inhibitor, toxicity, signaling, selective
Field of Research
Signal Transduction
Purity
98.21% (May vary between batches)
Solubility
2% DMSO+40% PEG300+5% Tween 80+53% Saline:1 mg/mL (1.9 mM) ; DMSO:11.9 mg/mL (22.56 mM)
Smiles
COc1cc (ccc1Nc1ncc2N (CC (F) (F) F) C (=O) c3ccccc3N (C) c2n1) N1CCN (C) CC1
Molecular Formula
C26H28F3N7O2
Molecular Weight
527.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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