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DCLK1-IN-1

DCLK1-IN-1 is a potent and selective chemical probe for DCLK1/2 kinase inhibition, with IC50 values in the low nanomolar range. This in vivo-compatible tool compound enables the investigation of DCLK1 biology and its functional roles in cancer models, both in vitro and in vivo.

Product Specifications

CAS Number

2222635-15-4

Product Name Alternative

Cancer, DCLK1IN1, DCLK-1-IN-1, DCLK1-IN-1, DCLK1 IN 1, PDAC, KRAS, inhibit, low, ERK, Inhibitor, toxicity, signaling, selective

Field of Research

Signal Transduction

Purity

98.21% (May vary between batches)

Solubility

2% DMSO+40% PEG300+5% Tween 80+53% Saline:1 mg/mL (1.9 mM) ; DMSO:11.9 mg/mL (22.56 mM)

Smiles

COc1cc (ccc1Nc1ncc2N (CC (F) (F) F) C (=O) c3ccccc3N (C) c2n1) N1CCN (C) CC1

Molecular Formula

C26H28F3N7O2

Molecular Weight

527.54

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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