Borussertib
Borussertib is a first-in-class, covalent-allosteric inhibitor of Akt kinase, exhibiting potent activity with an IC50 of 0.8 nM. It is a valuable research tool for studying Akt signaling in oncology, with applications in both in vitro biochemical assays and in vivo cancer models.
Product Specifications
CAS Number
1800070-77-2
Product Name Alternative
Borussertib, Akt (wt), Aktwt, Akt, inhibit, Inhibitor, Protein kinase B, PKB
Field of Research
Signal Transduction
Purity
98.18% (May vary between batches)
Solubility
DMSO:25 mg/mL (41.9 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.35 mM)
Smiles
C=CC (=O) Nc1ccc2[nH]c (=O) n (C3CCN (Cc4ccc (cc4) -c4nc5cc[nH]c (=O) c5cc4-c4ccccc4) CC3) c2c1
Molecular Formula
C36H32N6O3
Molecular Weight
596.68
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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