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Subasumstat

TAK-981 (Subasumstat) is a first-in-class, selective inhibitor of the SUMOylation cascade with demonstrated immune-activating and antitumor properties. It is utilized in oncology research to investigate SUMOylation's role in cancer immunity, showing activity in both cellular assays and in vivo tumor models.

Product Specifications

CAS Number

1858276-04-6

Product Name Alternative

Inhibit, Inhibitor, E3 ligating enzyme, E3 Enzyme, E2Enzyme, E2 conjugating enzyme, E2 Enzyme, E3Enzyme, E1 Enzyme, E1 activating enzyme, E1Enzyme, E1/E2/E3 Enzyme, Ubiquitin ligase, Ubiquitin conjugating enzyme, Ubiquitin activating enzyme, SUMOylation, Subasumstat, TAK981, TAK-981, TAK 981

Field of Research

Protein Biochemistry

Purity

97.02% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.46 mM) ; DMSO:122.5 mg/mL (211.9 mM)

Smiles

Cc1sc (cc1[C@@H]1NCCc2ccc (Cl) cc12) C (=O) c1cncnc1N[C@H]1C[C@H] (O) [C@@H] (COS (N) (=O) =O) C1

Molecular Formula

C25H28ClN5O5S2

Molecular Weight

578.1

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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