Subasumstat
TAK-981 (Subasumstat) is a first-in-class, selective inhibitor of the SUMOylation cascade with demonstrated immune-activating and antitumor properties. It is utilized in oncology research to investigate SUMOylation's role in cancer immunity, showing activity in both cellular assays and in vivo tumor models.
Product Specifications
CAS Number
1858276-04-6
Product Name Alternative
Inhibit, Inhibitor, E3 ligating enzyme, E3 Enzyme, E2Enzyme, E2 conjugating enzyme, E2 Enzyme, E3Enzyme, E1 Enzyme, E1 activating enzyme, E1Enzyme, E1/E2/E3 Enzyme, Ubiquitin ligase, Ubiquitin conjugating enzyme, Ubiquitin activating enzyme, SUMOylation, Subasumstat, TAK981, TAK-981, TAK 981
Field of Research
Protein Biochemistry
Purity
97.02% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.46 mM) ; DMSO:122.5 mg/mL (211.9 mM)
Smiles
Cc1sc (cc1[C@@H]1NCCc2ccc (Cl) cc12) C (=O) c1cncnc1N[C@H]1C[C@H] (O) [C@@H] (COS (N) (=O) =O) C1
Molecular Formula
C25H28ClN5O5S2
Molecular Weight
578.1
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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