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Senexin B

Senexin B is a potent, selective small-molecule inhibitor of CDK8 and CDK19, exhibiting dissociation constants (Kds) of 140 nM and 80 nM, respectively. It is a valuable research tool for studying the Mediator complex in oncology and inflammation, with utility in both cellular and in vivo models of cancer.

Product Specifications

CAS Number

1449228-40-3

Product Name Alternative

CDK19, CDK8, Senexin B

Field of Research

Cell Biology

Purity

99.63% (May vary between batches)

Solubility

DMSO:6 mg/mL (13.32 mM)

Smiles

CN1CCN (CC1) C (=O) c1ccc2cc (CCNc3ncnc4ccc (cc34) C#N) ccc2c1

Molecular Formula

C27H26N6O

Molecular Weight

450.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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