Senexin B
Senexin B is a potent, selective small-molecule inhibitor of CDK8 and CDK19, exhibiting dissociation constants (Kds) of 140 nM and 80 nM, respectively. It is a valuable research tool for studying the Mediator complex in oncology and inflammation, with utility in both cellular and in vivo models of cancer.
Product Specifications
CAS Number
1449228-40-3
Product Name Alternative
CDK19, CDK8, Senexin B
Field of Research
Cell Biology
Purity
99.63% (May vary between batches)
Solubility
DMSO:6 mg/mL (13.32 mM)
Smiles
CN1CCN (CC1) C (=O) c1ccc2cc (CCNc3ncnc4ccc (cc34) C#N) ccc2c1
Molecular Formula
C27H26N6O
Molecular Weight
450.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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