Dantrolene
Dantrolene is a postsynaptic muscle relaxant that acts by antagonizing ryanodine receptors, thereby inhibiting the release of Ca2+ from the sarcoplasmic reticulum. It is widely used in research applications, including in vitro muscle physiology studies and in vivo models of malignant hyperthermia and muscle spasticity.
Product Specifications
CAS Number
7261-97-4
Product Name Alternative
Dantrolene, calcium signaling, neuroleptic malignant syndrome, Inhibitor, inhibit, muscle spasticity, F 368, F368, F-368, glutathione reductase, Huntington's disease, malignant hyperthermia, Ryanodine receptor, ryanodine receptor
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery
Purity
99.97% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble) ; DMSO:22.5 mg/mL (71.6 mM)
Smiles
[O-][N+] (=O) c1ccc (cc1) -c1ccc (\C=N\N2CC (=O) NC2=O) o1
Molecular Formula
C14H10N4O5
Molecular Weight
314.25
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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