RET V804M-IN-1
RET V804M-IN-1 is a selective kinase inhibitor targeting wild-type RET with an IC50 of 20 nM, while also potently inhibiting the RET (V804M) gatekeeper mutant. This compound is a valuable chemical probe for investigating RET-driven oncogenesis in both cellular and biochemical assays.
Product Specifications
CAS Number
2414909-94-5
Product Name Alternative
RETV804M, RETV804M kinase inhibitor, RET V804M IN 1, RET V804MIN1, RET V-804M-IN-1, RET V804M-IN-1, RET, cRET, Inhibitor, inhibit, LUN 09945, LUN09945, LUN-09945
Field of Research
Cell Biology, Signal Transduction
Purity
96.97% (May vary between batches)
Solubility
DMSO:120 mg/mL (348.46 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.62 mM)
Smiles
NC (=O) c1ccc (cc1) -c1cnn2ccc (NCc3cccnc3) nc12
Molecular Formula
C19H16N6O
Molecular Weight
344.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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