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BMS-1001

BMS-1001 is a high-affinity small molecule inhibitor that potently blocks the PD-1/PD-L1 immune checkpoint interaction, demonstrating an IC50 of 2.25 nM. This inhibitor is a valuable tool for investigating cancer immunotherapy mechanisms in both biochemical and cellular assays, supporting research in oncology and immunology.

Product Specifications

CAS Number

2113650-03-4

Product Name Alternative

BMS1001, BMS-1001, BMS 1001, PD-1/PD-L1, PD1/PDL1, PD1, PD-1, PD-L1, PDL1

Field of Research

Cell Biology, Immunology & Inflammation

Purity

98.43% (May vary between batches)

Solubility

DMSO:5.95 mg/mL (10.01 mM)

Smiles

CC1=CC (CN[C@H] (CO) C (O) =O) =C (OCC2=CC (=CC=C2) C#N) C=C1OCC1=C (C) C (=CC=C1) C1=CC2=C (OCCO2) C=C1

Molecular Formula

C35H34N2O7

Molecular Weight

594.7

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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