BMS-1001
BMS-1001 is a high-affinity small molecule inhibitor that potently blocks the PD-1/PD-L1 immune checkpoint interaction, demonstrating an IC50 of 2.25 nM. This inhibitor is a valuable tool for investigating cancer immunotherapy mechanisms in both biochemical and cellular assays, supporting research in oncology and immunology.
Product Specifications
CAS Number
2113650-03-4
Product Name Alternative
BMS1001, BMS-1001, BMS 1001, PD-1/PD-L1, PD1/PDL1, PD1, PD-1, PD-L1, PDL1
Field of Research
Cell Biology, Immunology & Inflammation
Purity
98.43% (May vary between batches)
Solubility
DMSO:5.95 mg/mL (10.01 mM)
Smiles
CC1=CC (CN[C@H] (CO) C (O) =O) =C (OCC2=CC (=CC=C2) C#N) C=C1OCC1=C (C) C (=CC=C1) C1=CC2=C (OCCO2) C=C1
Molecular Formula
C35H34N2O7
Molecular Weight
594.7
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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