Tenovin-6 Hydrochloride
Tenovin-6 Hydrochloride is a small molecule inhibitor of SIRT1, SIRT2, and HDAC8 with reported IC50 values of 21 μM, 10 μM, and 67 μM, respectively. It functions as a p53 activator and has been utilized in both in vitro and in vivo cancer research studies to investigate pathways involving apoptosis and cellular senescence.
Product Specifications
CAS Number
1011301-29-3
Product Name Alternative
HDAC8, Inhibitor, MDM2, MDM-2/p53, inhibit, p53, Autophagy, acetylation, degradation, DHODH, Dihydroorotate Dehydrogenase, protein-deacetylating, SIRT2, SIRT1, Sirtuin, SIRT3, Tenovin6, Tenovin-6, Tenovin6 Hydrochloride, Tenovin-6 Hydrochloride, Tenovin 6, Tenovin 6 Hydrochloride
Field of Research
Cell Biology, Epigenetics & Chromatin, Metabolism Research, Molecular Biology
Purity
99.36% (May vary between batches)
Solubility
DMSO:45 mg/mL (91.63 mM)
Smiles
Cl.CN (C) CCCCC (=O) Nc1ccc (NC (=S) NC (=O) c2ccc (cc2) C (C) (C) C) cc1
Molecular Formula
C25H35ClN4O2S
Molecular Weight
491.09
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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