Ripretinib
Ripretinib (DCC-2618) is a small molecule research compound designed as an orally administered inhibitor targeting KIT and PDGFRA kinases. It is utilized in preclinical studies, including in vitro assays and in vivo models, for investigating gastrointestinal stromal tumors (GIST) and related oncogenic signaling pathways.
Product Specifications
CAS Number
1442472-39-0
Product Name Alternative
Apoptosis, CD117, CD135, c-Kit, cKit, Cluster of differentiation antigen 135, Platelet-derived growth factor receptor, Kit, inhibit, Inhibitor, Fms like tyrosine kinase 3, DCC-2618, DCC2618, DCC 2618, FLT3, SCFR, Ripretinib, PDGFR, Vascular endothelial growth factor receptor, VEGFR
Field of Research
Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.07% (May vary between batches)
Solubility
DMSO:41.67 mg/mL (81.65 mM) ;10% DMSO+90% Corn Oil:2 mg/mL (3.92 mM)
Smiles
CCn1c2cc (NC) ncc2cc (-c2cc (NC (=O) Nc3ccccc3) c (F) cc2Br) c1=O
Molecular Formula
C24H21BrFN5O2
Molecular Weight
510.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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