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GW6471

GW6471 is a potent PPARα antagonist (IC50 = 0.24 μM) that stabilizes co-repressor binding to the receptor. This tool compound is widely used in metabolic and cardiovascular research to inhibit PPARα-mediated transcription in both cellular and animal models.

Product Specifications

CAS Number

880635-03-0

Product Name Alternative

GW 6471, GW6471, GW-6471, inhibit, Inhibitor, PPARα, PPAR, Peroxisome proliferator-activated receptors

Field of Research

Metabolism Research, Molecular Biology

Purity

98.23% (May vary between batches)

Solubility

DMSO:16.67 mg/mL (26.9 mM) ;10% DMSO+90% Saline:0.25 mg/mL (0.4 mM)

Smiles

CCC (=O) NC[C@H] (Cc1ccc (OCCc2nc (oc2C) -c2ccccc2) cc1) N\C (C) =C/C (=O) c1ccc (cc1) C (F) (F) F

Molecular Formula

C35H36F3N3O4

Molecular Weight

619.67

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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