GW6471
GW6471 is a potent PPARα antagonist (IC50 = 0.24 μM) that stabilizes co-repressor binding to the receptor. This tool compound is widely used in metabolic and cardiovascular research to inhibit PPARα-mediated transcription in both cellular and animal models.
Product Specifications
CAS Number
880635-03-0
Product Name Alternative
GW 6471, GW6471, GW-6471, inhibit, Inhibitor, PPARα, PPAR, Peroxisome proliferator-activated receptors
Field of Research
Metabolism Research, Molecular Biology
Purity
98.23% (May vary between batches)
Solubility
DMSO:16.67 mg/mL (26.9 mM) ;10% DMSO+90% Saline:0.25 mg/mL (0.4 mM)
Smiles
CCC (=O) NC[C@H] (Cc1ccc (OCCc2nc (oc2C) -c2ccccc2) cc1) N\C (C) =C/C (=O) c1ccc (cc1) C (F) (F) F
Molecular Formula
C35H36F3N3O4
Molecular Weight
619.67
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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