Empesertib
Empesertib (BAY 1161909) is a potent and selective oral Mps1 inhibitor (IC50 < 1 nM) with antineoplastic potential. It is used in cancer research to study mitotic checkpoint inhibition, demonstrating antitumor activity in both cellular assays and in vivo xenograft models.
Product Specifications
CAS Number
1443763-60-7
Product Name Alternative
BAY 1161909, BAY1161909, BAY-1161909, Empesertib, Inhibitor, inhibit, Mps1, Monopolar spindle 1
Field of Research
Signal Transduction
Purity
97.45% (May vary between batches)
Solubility
DMSO:10 mg/mL (17.87 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.79 mM)
Smiles
COc1cc (ccc1Nc1nc2ccc (cn2n1) -c1ccc (NC (=O) [C@H] (C) c2ccc (F) cc2) cc1) S (C) (=O) =O
Molecular Formula
C29H26FN5O4S
Molecular Weight
559.61
Storage Conditions
-20°C
Notes
For research use only.
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