Vorolanib
Vorolanib (X-82) is an orally active dual inhibitor of VEGFR and PDGFR used in research on angiogenesis, particularly in oncology and ophthalmology. Studies report its activity in in vitro cell-based assays and in vivo tumor and ocular neovascularization models, based on publicly available literature.
Product Specifications
CAS Number
1013920-15-4
Product Name Alternative
ABC, ABCG2, angiogenesis, ATP-binding, CM082, CM 082, CM-082, cassette, inhibit, kinase, orally, Platelet-derived growth factor receptor, Inhibitor, HUVECs, X 82, X82, X-82, TKI, PDGFR, Vascular endothelial growth factor receptor, VEGFR, Vorolanib, transporter, tyrosine
Field of Research
Cardiovascular Research, Signal Transduction
Purity
97.35% (May vary between batches)
Solubility
DMSO:22 mg/mL (50.06 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.55 mM)
Smiles
CN (C) C (=O) N1CC[C@@H] (C1) NC (=O) c1c (C) [nH]c (\C=C2\C (=O) Nc3ccc (F) cc23) c1C
Molecular Formula
C23H26FN5O3
Molecular Weight
439.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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