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Vorolanib

Vorolanib (X-82) is an orally active dual inhibitor of VEGFR and PDGFR used in research on angiogenesis, particularly in oncology and ophthalmology. Studies report its activity in in vitro cell-based assays and in vivo tumor and ocular neovascularization models, based on publicly available literature.

Product Specifications

CAS Number

1013920-15-4

Product Name Alternative

ABC, ABCG2, angiogenesis, ATP-binding, CM082, CM 082, CM-082, cassette, inhibit, kinase, orally, Platelet-derived growth factor receptor, Inhibitor, HUVECs, X 82, X82, X-82, TKI, PDGFR, Vascular endothelial growth factor receptor, VEGFR, Vorolanib, transporter, tyrosine

Field of Research

Cardiovascular Research, Signal Transduction

Purity

97.35% (May vary between batches)

Solubility

DMSO:22 mg/mL (50.06 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.55 mM)

Smiles

CN (C) C (=O) N1CC[C@@H] (C1) NC (=O) c1c (C) [nH]c (\C=C2\C (=O) Nc3ccc (F) cc23) c1C

Molecular Formula

C23H26FN5O3

Molecular Weight

439.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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