BO-264
BO-264 is a potent, orally bioavailable small molecule inhibitor of TACC3, demonstrating high affinity with a Kd of 1.5 nM and an IC50 of 188 nM. It serves as a valuable chemical probe for investigating TACC3 function in cancer biology research, supporting both in vitro and in vivo experimental studies.
Product Specifications
CAS Number
2408648-20-2
Product Name Alternative
DNA, damage, cytotoxicity, abnormalities, BO264, BO-264, BO 264, antitumor, anti-proliferative, Apoptosis, mitotic, Inhibitor, inhibit, ERK1/2, Fibroblast growth factor receptor, FGFR, FGFR3-TACC3, phosphorylation, TACC3, spindle
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
>98%
Bioactivity
TACC3 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to at least 25 mg/ml)
Smiles
COc1ccc (cc1) -c1cc (Nc2ccnc (n2) N2CCOCC2) on1
Molecular Formula
C18H19N5O3
Molecular Weight
353.4
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
3- (4-Methoxyphenyl) -N- (2-morpholin-4-ylpyrimidin-4-yl) -1,2-oxazol-5-amine
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