SC-236
SC-236 is a potent and selective COX-2 inhibitor, demonstrating high oral activity. It exhibits significant selectivity with an IC50 of 0.005 μM for COX-2 versus 17.8 μM for COX-1. This compound is widely used in research models of inflammation, pain, and cancer, both in vitro and in vivo.
Product Specifications
CAS Number
170569-86-5
Product Name Alternative
SC 236, Sc 236, SC236, SC-236, TNF-α, Peroxisome proliferator-activated receptors, PPAR, fibrogenesis, gastric, fibrosis, Inhibitor, neuroprotection, inhibit, ischemia, Liver, allodynia, cancer, Apoptosis, COX, COX-2, Cyclooxygenase
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Molecular Biology, Neuroscience
Purity
98.00% (May vary between batches)
Solubility
DMSO:22.5 mg/mL (56 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.98 mM)
Smiles
NS (=O) (=O) c1ccc (cc1) -n1nc (cc1-c1ccc (Cl) cc1) C (F) (F) F
Molecular Formula
C16H11ClF3N3O2S
Molecular Weight
401.79
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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