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THPP-1

THPP-1 is a highly potent, orally bioavailable PDE10A inhibitor with Ki values of 1 nM (human) and 1.3 nM (rat) . This small molecule is a valuable research tool for investigating PDE10A function in neuropsychiatric disorders, enabling both in vitro biochemical assays and in vivo pharmacological studies.

Product Specifications

CAS Number

1257051-63-0

Product Name Alternative

Novel, inhibit, object, PDE10A, Inhibitor, THPP 1, THPP1, THPP-1, SIMA, recognition, Phosphodiesterase (PDE), phosphodiesterase

Field of Research

Metabolism Research

Purity

99.23% (May vary between batches)

Solubility

DMSO:31 mg/mL (66.68 mM)

Smiles

COCCOc1nc (nc2CCN (Cc12) C (=O) c1ncn2ccccc12) -c1ccc (Cl) nc1

Molecular Formula

C23H21ClN6O3

Molecular Weight

464.9

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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