Spastazoline
Spastazoline is a potent and selective small molecule inhibitor of human spastin, exhibiting an IC50 of 99 nM. This compound is a valuable research tool for studying microtubule dynamics and has been utilized in cellular models to investigate the role of spastin in hereditary spastic paraplegia.
Product Specifications
CAS Number
2351882-11-4
Product Name Alternative
Vesicle transport, Spastazoline, spastin, selective, HeLa, inhibit, Inhibitor, microtubule-severing, division, cell division, AAA protein
Field of Research
Cell Biology, Neuroscience
Purity
>98%
Bioactivity
Spastin inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) .
Smiles
CC (C) [C@@H]1CN (CCN1) c1nc (Nc2cc ([nH]n2) C (C) (C) C) c2cc[nH]c2n1
Molecular Formula
C20H30N8
Molecular Weight
382.5
Storage Conditions
RT
Notes
For research use only.
Other Product Names
N- (5-tert-Butyl-1H-pyrazol-3-yl) -2-[ (3R) -3-propan-2-ylpiperazin-1-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Available Sizes
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