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Spastazoline

Spastazoline is a potent and selective small molecule inhibitor of human spastin, exhibiting an IC50 of 99 nM. This compound is a valuable research tool for studying microtubule dynamics and has been utilized in cellular models to investigate the role of spastin in hereditary spastic paraplegia.

Product Specifications

CAS Number

2351882-11-4

Product Name Alternative

Vesicle transport, Spastazoline, spastin, selective, HeLa, inhibit, Inhibitor, microtubule-severing, division, cell division, AAA protein

Field of Research

Cell Biology, Neuroscience

Purity

>98%

Bioactivity

Spastin inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 25 mg/ml) .

Smiles

CC (C) [C@@H]1CN (CCN1) c1nc (Nc2cc ([nH]n2) C (C) (C) C) c2cc[nH]c2n1

Molecular Formula

C20H30N8

Molecular Weight

382.5

Storage Conditions

RT

Notes

For research use only.

Other Product Names

N- (5-tert-Butyl-1H-pyrazol-3-yl) -2-[ (3R) -3-propan-2-ylpiperazin-1-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Available Sizes

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