LML134
LML134 (LML-134) is a potent and selective inverse agonist of the human Histamine H3 Receptor (H3R), demonstrating high affinity with Kis of 0.3 nM in cAMP assays and 12 nM in binding assays. This small molecule is a valuable research tool for investigating H3R function in neurological disorders, supporting both in vitro mechanistic studies and in vivo preclinical research.
Product Specifications
CAS Number
1542135-76-1
Product Name Alternative
H3 receptor, Histamine Receptor, HistamineReceptor, Inhibitor, LML 134, LML134, LML-134, inhibit
Field of Research
Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery
Purity
99.36% (May vary between batches)
Solubility
DMSO:7.5 mg/mL (19.97 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.66 mM)
Smiles
Cn1nc (ccc1=O) N1CCC (CC1) OC (=O) N1CCN (CC1) C1CCC1
Molecular Formula
C19H29N5O3
Molecular Weight
375.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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