Metformin
Metformin (1,1-Dimethylbiguanide) is a blood-brain barrier permeable AMPK activator used in type 2 diabetes research. It improves glycemic control by enhancing insulin sensitivity and reducing intestinal glucose absorption. This compound is widely applied in metabolic disease studies, including in vitro mechanistic investigations and in vivo animal models.
Product Specifications
CAS Number
657-24-9
Product Name Alternative
Diabetes, chain, AMPK, Autophagy, barrier, blood-brain, AMP-activated protein kinase, 1,1-Dimethylbiguanide, inhibit, liver, Mitophagy, mitochondrial, Mitochondrial Autophagy, Metformin, insulin, Inhibitor, sensitivity, respiratory, type
Field of Research
Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
H2O:100 mg/mL (774.23 mM) ; DMSO:49 mg/mL (379.37 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (15.48 mM)
Smiles
CN (C) C (=N) NC (N) =N
Molecular Formula
C4H11N5
Molecular Weight
129.16
Storage Conditions
-20°C
Notes
For research use only.
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