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Metformin

Metformin (1,1-Dimethylbiguanide) is a blood-brain barrier permeable AMPK activator used in type 2 diabetes research. It improves glycemic control by enhancing insulin sensitivity and reducing intestinal glucose absorption. This compound is widely applied in metabolic disease studies, including in vitro mechanistic investigations and in vivo animal models.

Product Specifications

CAS Number

657-24-9

Product Name Alternative

Diabetes, chain, AMPK, Autophagy, barrier, blood-brain, AMP-activated protein kinase, 1,1-Dimethylbiguanide, inhibit, liver, Mitophagy, mitochondrial, Mitochondrial Autophagy, Metformin, insulin, Inhibitor, sensitivity, respiratory, type

Field of Research

Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction

Purity

98.00% (May vary between batches)

Solubility

H2O:100 mg/mL (774.23 mM) ; DMSO:49 mg/mL (379.37 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (15.48 mM)

Smiles

CN (C) C (=N) NC (N) =N

Molecular Formula

C4H11N5

Molecular Weight

129.16

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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