CPYPP
CPYPP is a cell-permeable small molecule inhibitor that selectively targets the DHR-2 domain of DOCK2, blocking its Rac1-GEF activity with an IC50 of 22.8 μM. It also inhibits related DOCK family members DOCK180 and DOCK5. This compound is a valuable research tool for studying Rac1-mediated signaling in immune cell migration and cancer metastasis in both cellular and animal models.
Product Specifications
CAS Number
310460-39-0
Product Name Alternative
DOCK9, DOCK180, DOCK2, DOCK2-Rac1, DOCK5, CPYPP, autoimmune, lymphocytes, Inhibitor, immunosuppressant, inhibit, migration, GEF, Rac1
Purity
98.28% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.16 mM) ; DMSO:23 mg/mL (70.82 mM)
Smiles
Clc1ccccc1\C=C\C=C1/C (=O) NN (C1=O) c1ccccc1
Molecular Formula
C18H13ClN2O2
Molecular Weight
324.76
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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