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ML318

ML318 is a potent biaryl nitrile inhibitor of the PvdQ acylase, exhibiting an IC50 of 20 nM. It effectively suppresses Pseudomonas aeruginosa (PAO1) growth (IC50 = 19 μM) and pyoverdine siderophore production, particularly under iron-limiting conditions, making it a valuable tool for studying quorum sensing and virulence pathways in vitro.

Product Specifications

CAS Number

1610516-67-0

Product Name Alternative

Acylase, acyl-binding, Antibiotic, PAO1, ML 318, ML318, ML-318, PvdQ, PvdQ acylase, iron, inhibit, Inhibitor, production, site, pyoverdine, P.aeruginosa

Field of Research

Infectious Disease & Virology

Purity

98.65% (May vary between batches)

Solubility

DMSO:60 mg/mL (214.12 mM)

Smiles

Fc1ccc (cc1) C (C#N) c1cccc (n1) C (F) (F) F

Molecular Formula

C14H8F4N2

Molecular Weight

280.22

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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