ML318
ML318 is a potent biaryl nitrile inhibitor of the PvdQ acylase, exhibiting an IC50 of 20 nM. It effectively suppresses Pseudomonas aeruginosa (PAO1) growth (IC50 = 19 μM) and pyoverdine siderophore production, particularly under iron-limiting conditions, making it a valuable tool for studying quorum sensing and virulence pathways in vitro.
Product Specifications
CAS Number
1610516-67-0
Product Name Alternative
Acylase, acyl-binding, Antibiotic, PAO1, ML 318, ML318, ML-318, PvdQ, PvdQ acylase, iron, inhibit, Inhibitor, production, site, pyoverdine, P.aeruginosa
Field of Research
Infectious Disease & Virology
Purity
98.65% (May vary between batches)
Solubility
DMSO:60 mg/mL (214.12 mM)
Smiles
Fc1ccc (cc1) C (C#N) c1cccc (n1) C (F) (F) F
Molecular Formula
C14H8F4N2
Molecular Weight
280.22
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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