BMS-345541
BMS-345541 hydrochloride is a potent and selective inhibitor of IκB kinase (IKK), exhibiting greater potency against IKK2 (IC50 = 0.3 μM) than IKK1 (IC50 = 4 μM) . This small molecule is widely used in research to investigate NF-κB signaling pathways in cellular models and has been applied in animal studies to explore inflammation and oncology.
Product Specifications
CAS Number
547757-23-3
Product Name Alternative
IkB/IKK, IkB, IKK, IKK1, IKK2, Inhibitor, I kappa B kinase, inhibit, IκB, IκB kinase, BMS345541, BMS-345541, BMS345541 hydrochloride, BMS345541 Hydrochloride, BMS-345541 Hydrochloride, BMS 345541, BMS 345541 Hydrochloride, BMS 345541 hydrochloride
Field of Research
Immunology & Inflammation
Purity
>98%
Bioactivity
IkappaB kinase inhibitor; prevents NFkB activation
Form
Powder
Solubility
DMSO:18 mg/mL (61.69 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.85 mM)
Smiles
Cl.Cc1cnc2c (NCCN) nc3ccc (C) cc3n12
Molecular Formula
C14H18ClN5
Molecular Weight
291.78
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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