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NDMC101

NDMC101 is a small molecule research compound that functions as a dual inhibitor of dipeptidyl peptidase-IV (DPP-IV) in T cells and the transcription factors NFATc1 and NF-κB, thereby demonstrating immunomodulatory properties. Its applications include in vitro studies of T-cell activation and inflammation, as well as in vivo research on autoimmune and inflammatory disease models.

Product Specifications

CAS Number

1308631-40-4

Product Name Alternative

Dipeptidyl Peptidase, DPP, Bone, bone destruction, marrow-derived macrophages, Inhibitor, inhibit, NSAID, Nuclear factor-kappaB, Nuclear factor-κB, osteoblast, osteoclastogenesis, NF-κB, NFκB, NFkB, NF-kB, NDMC 101, NDMC101, NDMC-101, synovial inflammation, rheumatoid arthritis, RAW 264.7

Field of Research

Protein Biochemistry, Signal Transduction

Purity

99.59% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.53 mM) ; DMSO:11 mg/mL (41.4 mM)

Smiles

Oc1ccccc1C (=O) Nc1ccc (Cl) cc1F

Molecular Formula

C13H9ClFNO2

Molecular Weight

265.67

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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