BC-1382
BC-1382 is a potent and selective small molecule inhibitor of the HECTD2 E3 ubiquitin ligase, disrupting its interaction with PIAS1 with an IC50 of 5 nM. This tool compound enables the study of HECTD2-mediated ubiquitination in cellular and biochemical assays, facilitating research into related signaling pathways and protein homeostasis.
Product Specifications
CAS Number
1013753-99-5
Product Name Alternative
Ubiquitin E3 ligase HECTD2, Ubiquitin conjugating enzyme, Ubiquitin ligase, Ubiquitin activating enzyme, Ubiquitin, BC1382, BC-1382, BC 1382, E1Enzyme, E1/E2/E3 Enzyme, E2 conjugating enzyme, E1 activating enzyme, E1 Enzyme, E2 Enzyme, E2Enzyme, E3 Enzyme, E3Enzyme, E3 ligating enzyme, lung, Inhibitor, ligase, inhibit, inflammation, HECTD2, HECTD2/PIAS1, interaction, Anti-inflammatory
Field of Research
Protein Biochemistry
Purity
99.15% (May vary between batches)
Solubility
DMSO:55 mg/mL (119.68 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.35 mM)
Smiles
COc1ccccc1CNC (=O) C (C) NC (=O) C1CCN (CC1) S (=O) (=O) c1ccccc1
Molecular Formula
C23H29N3O5S
Molecular Weight
459.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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