Nav1.8-IN-1
Nav1.8-IN-1 is a selective small molecule inhibitor of the human voltage-gated sodium channel NaV1.8 (SCN10A) . This compound is a valuable research tool for investigating NaV1.8's role in pain signaling and is suitable for both in vitro electrophysiology studies and in vivo preclinical models of neuropathic and inflammatory pain.
Product Specifications
CAS Number
1026822-49-0
Product Name Alternative
Inhibitor, Nav1.8 channel, Nav1.8 IN 1, Nav1.8IN1, Nav1.8-IN-1, neuropathic pain, Na channels, Na+ channels, Na (v) 1.8, inhibit, inflammatory, 5- (4-Chlorophenyl) -N-[[2- (2,2,2-trifluoroethoxy) pyridin-3-yl]methyl]pyridine-3-carboxamide, CHEMBL1270208, CHEMBL-1270208, CHEMBL 1270208, Sodium Channel, SodiumChannel
Field of Research
Pharmacology & Drug Discovery
Purity
96.38% (May vary between batches)
Solubility
DMSO:10 mg/mL (23.71 mM)
Smiles
C (NCC1=C (OCC (F) (F) F) N=CC=C1) (=O) C2=CC (=CN=C2) C3=CC=C (Cl) C=C3
Molecular Formula
C20H15ClF3N3O2
Molecular Weight
421.8
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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