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α-Fluoromethylhistidine (dihydrochloride)

α-Fluoromethylhistidine dihydrochloride s a potent histidine decarboxylase (HD) inhibitor used in studies to reduce histamine levels[1].

Product Specifications

CAS Number

[81839-27-2]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Amino Acid Decarboxylase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/α-fluoromethylhistidine-dihydrochloride.html

Purity

99.1

Smiles

N[C@](CC1=CNC=N1)(CF)C(O)=O.Cl.Cl

Molecular Formula

C7H12Cl2FN3O2

Molecular Weight

260.09

Precautions

H302, H315, H319, H335

References & Citations

[1]Garbarg M, et al. Inhibition of histamine synthesis in brain by alpha-fluoromethylhistidine, a new irreversible inhibitor: in vitro and in vivo studies. J Neurochem. 1980 Nov;35 (5) :1045-52.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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