α-Fluoromethylhistidine (dihydrochloride)
α-Fluoromethylhistidine dihydrochloride s a potent histidine decarboxylase (HD) inhibitor used in studies to reduce histamine levels[1].
Product Specifications
CAS Number
[81839-27-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Amino Acid Decarboxylase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/α-fluoromethylhistidine-dihydrochloride.html
Purity
99.1
Smiles
N[C@](CC1=CNC=N1)(CF)C(O)=O.Cl.Cl
Molecular Formula
C7H12Cl2FN3O2
Molecular Weight
260.09
Precautions
H302, H315, H319, H335
References & Citations
[1]Garbarg M, et al. Inhibition of histamine synthesis in brain by alpha-fluoromethylhistidine, a new irreversible inhibitor: in vitro and in vivo studies. J Neurochem. 1980 Nov;35 (5) :1045-52.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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