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Onjisaponin B

Onjisaponin B is a research compound that activates autophagy through the AMPK-mTOR pathway, elevates NGF, and enhances clearance of mutant huntingtin and A53T α-synuclein. It is utilized in preclinical studies for neurodegenerative disease research, including Parkinson's, Alzheimer's, and Huntington's disease models.

Product Specifications

CAS Number

35906-36-6

Product Name Alternative

AMPK, Autophagy, Inhibitor, Onjisaponin B, inhibit, mTOR, PGE

Field of Research

Cell Biology, Epigenetics & Chromatin, Neuroscience, Protein Biochemistry, Signal Transduction

Purity

99.20% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (1.27 mM) ; DMSO:50 mg/mL (31.77 mM)

Smiles

[H][C@@]1 (O[C@H]2[C@H] (C) O[C@@] ([H]) (O[C@H]3[C@H] (OC (=O) [C@]45CCC (C) (C) C[C@@]4 ([H]) C4=CC[C@]6 ([H]) [C@@]7 (C) C[C@H] (O) [C@H] (O[C@]8 ([H]) O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]8O) [C@@] (C) (C (O) =O) [C@]7 ([H]) CC[C@@]6 (C) [C@]4 (CO) CC5) O[C@H] (C) [C@H] (OC (=O) \C=C\c4ccc (OC) cc4) [C@@H]3O[C@]3 ([H]) O[C@@H] (C) [C@H] (O) [C@@H] (O) [C@H]3O) [C@H] (O) [C@@H]2O) OC[C@@H] (O[C@]2 ([H]) O[C@H] (CO) [C@H] (O) [C@H] (O) [C@H]2O) [C@H] (O) [C@H]1O

Molecular Formula

C75H112O35

Molecular Weight

1573.67

Storage Conditions

Store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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