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11-​Keto-​beta-​boswellic acid

11-Keto-beta-boswellic acid is a dual-activity small molecule that activates the Nrf2 pathway and selectively inhibits 5-lipoxygenase (5-LOX) . It demonstrates a dose-dependent cardioprotective effect, as evidenced by reduced serum lactate dehydrogenase levels in research models. This compound is used in studies investigating oxidative stress, inflammation, and cardiovascular protection in both cellular and animal systems.

Product Specifications

CAS Number

17019-92-0

Product Name Alternative

PI3K, inhibit, Lipoxygenase, LOX, NFκB, NF-κB, NO Synthase, Nuclear factor-κB, Nuclear factor-kappaB, NF-kB, NFkB, Inhibitor, LeukotrieneReceptor, leukotriene receptor, Leukotriene Receptor, Akt, 5-LOX, 11​Keto​beta​boswellic acid, 11 ​Keto ​beta ​boswellic acid, 11-Keto-β-boswellic acid, 11-Keto-b-boswellic acid, 11-Keto-beta-boswellic acid

Field of Research

Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Purity

99.68% (May vary between batches)

Solubility

DMSO:22.5 mg/mL (47.8 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.25 mM)

Smiles

[H][C@@]12[C@@H] (C) [C@H] (C) CC[C@]1 (C) CC[C@]1 (C) C2=CC (=O) [C@]2 ([H]) [C@@]3 (C) CC[C@@H] (O) [C@] (C) (C (O) =O) [C@]3 ([H]) CC[C@@]12C

Molecular Formula

C30H46O4

Molecular Weight

470.68

Storage Conditions

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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