3'-Demethylnobiletin

3'-Demethylnobiletin is a bioactive flavonoid with demonstrated chemopreventive potential against colon cancer. In vitro studies show it inhibits colon cancer cell proliferation, induces cell-cycle arrest and apoptosis, while in vivo models support its anti-carcinogenic activity in the colon.

Product Specifications

CAS Number

112448-39-2

Product Name Alternative

RNA Synthesis, RNASynthesis, DNASynthesis, DNA Synthesis, CD36, 3' Demethylnobiletin, 3'Demethylnobiletin, 3'-Demethylnobiletin, AP-1, LDL, Inhibitor, LOX, inhibit, NF-kB, NFkB, NF-κB, NFκB

Field of Research

Cardiovascular Research, Cell Biology, Metabolism Research, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.75% (May vary between batches)

Solubility

DMSO:80 mg/mL (205.99 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.5 mM)

Smiles

O (C) C1=C2C (=C (OC) C (OC) =C1OC) OC (=CC2=O) C3=CC (O) =C (OC) C=C3

Molecular Formula

C20H20O8

Molecular Weight

388.37

Storage Conditions

Store at low temperature, keep away from direct sunlight, keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.